How to let go...?

Oh dear. I have printed out copies of the ms for my three early readers, I have punched holes in two of them. And every time I glance at it I see something that needs changing. I know I can't really tell piecemeal, but it's so very, very hard to hand something over unless you're feeling for the moment (however wrongly) you've got it right. However, I know I need more distance before I can work on it again, and this is the only window two of my readers have.  I'm going to find this really difficult...